D3 40000 IU Capsule 4pcs

Composition of D3 40000 IU Capsule

Cholecalciferol [Vitamin D3]

Uses of D3 40000 IU Capsule

Treatment of Osteoporosis, Osteomalacia (Rickets), Vitamin D deficiency, Hypoparathyroidism, and Latent tetany.

Side Effects of D3 40000 IU Capsule

• Increased blood calcium levels
• Increased calcium levels in urine
• Confusion
• Constipation
• Skin rash, hives, or itching

Benefits of D3 40000 IU Capsule

• D3 40000 IU Capsule helps in maintaining healthy bones and teeth
• Vitamin D helps to boost the immune system
• The capsule helps in the higher absorption of calcium
• D3 40000 IU Capsule helps reduce fatigue/stress and muscular pains
• D3 40000 IU Capsule helps your body absorb calcium and phosphorus from food and supplements, which are essential for maintaining strong bones and teeth.

Vitamin D Deficiency

Vitamin D is essential for your body’s health. D3 40000 IU Capsule helps treat vitamin D deficiency, ensuring your body gets the necessary amount of this crucial nutrient.

Osteoporosis

D3 40000 IU Capsule is used to manage osteoporosis, a condition where bones become fragile due to calcium deficiency.

Osteomalacia and Rickets

D3 40000 IU Capsule is also effective in treating osteomalacia and rickets, conditions caused by vitamin D deficiency that result in soft, weak bones in adults and children.

Hypoparathyroidism

In cases of hypoparathyroidism, where low levels of parathyroid hormone lead to calcium imbalance, D3 40000 IU Capsule helps restore calcium levels.

Pharmacology

The active form of Vitamin D3, known as Calcitriol, functions by binding to Vitamin D receptors (VDRs), which are present in various body tissues. Vitamin D3, being fat-soluble, has a half-life of approximately 50 days. After being absorbed in the small intestine, it binds to specific alpha-globulins and is transported to the liver, where it is metabolized into 25-hydroxy Vitamin D3 (Calcidiol). This is further hydroxylated in the kidneys to 1,25-dihydroxy Vitamin D3 (Calcitriol), the form that enhances calcium absorption. Unmetabolized Vitamin D3 is stored in fat and muscle tissues and is eventually eliminated through feces and urine.

Dosage of D3 40000 IU Capsule

Adults:

Treatment of Vitamin D3 Deficiency: 40,000 IU once weekly for 7 weeks. Maintenance dose: 1,400-2,000 IU daily. Check 25-hydroxyvitamin D levels 3-4 months after starting maintenance therapy.

Prevention of Vitamin D3 Deficiency: 20,000 IU every 4 weeks, with higher doses possibly needed in certain cases.

Osteoporosis Therapy (with other treatments): 20,000 IU once a month.

Children (12-18 years):

Treatment of Vitamin D3 Deficiency: 20,000 IU every 2 weeks for 6 weeks.

Prevention of Vitamin D3 Deficiency: 20,000 IU every 6 weeks.

Administration of D3 40000 IU Capsule

Take D3 40000 IU Capsule as advised by your physician. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. Swallow D3 40000 IU Capsule with a glass of water. Do not crush or chew the medicine.

Interaction of D3 40000 IU Capsule

Drug-Drug Interactions: D3 40000 IU Capsule may interact with certain medications, including cholesterol-lowering drugs (cholestyramine), anti-epileptics (carbamazepine, phenobarbital), certain antibiotics (doxycycline, neomycin, chloramphenicol), bone loss medications (alendronate), thyroid hormones (levothyroxine), diuretics (hydrochlorothiazide), and heart medications (digoxin).

Drug-Food Interactions: Limit or avoid caffeine, soft drinks, and alcohol, as they can interfere with calcium absorption.

Drug-Disease Interactions: D3 40000 IU Capsule is contraindicated in conditions such as hypercalcemia, hyperparathyroidism, hypervitaminosis D, malabsorption syndrome, Vitamin D toxicity, and in individuals with heart, kidney, liver, or blood vessel diseases, kidney stones, diabetes, or phenylketonuria.

Not Recommended For Use In:

• High calcium levels in blood (hypercalcemia) or urine (hypercalciuria)
• Liver problems
• Kidney failure or kidney stones
• High levels of vitamin D in the blood (hypervitaminosis D)

Pregnancy & Lactation

Should be used cautiously in pregnant or breastfeeding women, as excessive vitamin D can harm the baby.

Precautions & Warnings

Before taking the D3 40000 IU Capsule, inform your physician if you have any allergies to it. If you are diabetic or have phenylketonuria, be cautious with chewable or dissolvable tablets as they may contain sugar or aspartame. Pregnant or breastfeeding women should consult their doctor before use, as higher doses of Vitamin D should only be taken if advised by a healthcare professional. D3 40000 IU Capsule can pass into breast milk, so breastfeeding mothers should seek medical advice before starting the supplement. Use with caution in cases of hypercalcemia, hyperparathyroidism, renal impairment, electrolyte imbalance, heart disease, kidney stones, and hypervitaminosis D.

Storage Conditions:

• Keep the medicine out of reach of children
• Store D3 40000 IU Capsule at room temperature